International Publications

Boeckxstaens P, Vaes B, De Sutter A, Aujoulat I, van Pottelbergh G, Matheï C, Degryse JM. A High Sense of Coherence as Protection Against Adverse Health Outcomes in Patients Aged 80 Years and Older.

Ann Fam Med. 2016 Jul;14(4):337-43.


Hegendörfer E, Vaes B, Andreeva E, Matheï C, Van Pottelbergh G, Degryse JM.Predictive Value of Different Expressions of Forced Expiratory Volume in 1 Second (FEV1) for Adverse Outcomes in a Cohort of Adults Aged 80 and Older.

J Am Med Dir Assoc. 2017 Feb


Smeets M, Degryse J, Janssens S, Matheï C, Wallemacq P, Vanoverschelde JL, Aertgeerts B, Vaes B. Diagnostic rules and algorithms for the diagnosis of non-acute heart failure in patients 80 years of age and older: a diagnostic accuracy and validation study. BMJ Open. 2016 Oct 6;6


Adriaensen W, Pawelec G, Vaes B, Hamprecht K, Derhovanessian E, van Pottelbergh G, Degryse JM, Matheï C. CD4:8 Ratio Above 5 Is Associated With All-Cause Mortality in CMV-Seronegative Very Old Women: Results From the BELFRAIL Study.

J Gerontol A Biol Sci Med Sci. 2016 Dec 7


Wauters M, Elseviers M, Vaes B, Degryse J, Dalleur O, Vander Stichele R, Christiaens T, Azermai M. Too many, too few, or too unsafe? Impact of inappropriate prescribing on mortality, and hospitalization in a cohort of community-dwelling oldest oldBr J Clin Pharmacol. 2016 Nov;82(5):1382-1392. doi: 10.1111/bcp.13055


Wauters M, Klamer T, Elseviers M, Vaes B, Dalleur O, Degryse J, Durán C, Christiaens T, Azermai M, Vander Stichele R. Anticholinergic Exposure in a cohort of adults aged 80 years and over Associations of the MARANTE scale with mortality and hospitalisation.

Basic Clin Pharmacol Toxicol. 2016 Dec 20. 

Wauters M, Elseviers M, Vaes B, Degryse J, Dalleur O, Vander SR et al. Polypharmacy in a Belgian cohort of community-dwelling oldest old (80+). Acta Clin Belg 2016;1-9.


Wauters M, Elseviers M, Vaes B, Degryse J, Vander SR, Christiaens T et al. Mortality, hospitalisation, institutionalisation in community-dwelling oldest old: The impact of medication. Arch Gerontol Geriatr 2016; 65:9-16.


Rezzoug N, Vaes B, de MC, Degryse J, Van PG, Mathei C et al. The clinical impact of valvular heart disease in a population-based cohort of subjects aged 80 and older. BMC Cardiovasc Disord 2016; 16:7.


Dalleur O, Boland B, De GA, Vaes B, Boeckxstaens P, Azermai M et al. Detection of potentially inappropriate prescribing in the very old: cross-sectional analysis of the data from the BELFRAIL observational cohort study. BMC Geriatr 2015; 15:156.


Rezzoug N, Vaes B, Pasquet A, Gerber B, de MC, Van PG et al. Prevalence and Prognostic Impact of Valve Area-Gradient Patterns in Patients >/=80 Years With Moderate-to-Severe Aortic Stenosis (from the Prospective BELFRAIL Study). Am J Cardiol 2015; 116(6):925-932.


Turkeshi E, Zelenukha D, Vaes B, Andreeva E, Frolova E, Degryse JM. Predictors of poor-quality spirometry in two cohorts of older adults in Russia and Belgium: a cross-sectional study. NPJ Prim Care Respir Med 2015; 25:15048.


Adriaensen W, Mathei C, Vaes B, Van PG, Wallemacq P, Degryse JM. Interleukin-6 as a first-rated serum inflammatory marker to predict mortality and hospitalization in the oldest old: A regression and CART approach in the BELFRAIL study. Exp Gerontol 2015; 69:53-61.


Smeets M, Degryse J, Aertgeerts B, Janssens S, Adriaensen W, Mathei C et al. General practitioners' judgement of chronic heart failure in the oldest old: Insights from the BELFRAIL study. Int J Cardiol 2015; 191:120-127.


Turkeshi E, Vaes B, Andreeva E, Mathei C, Adriaensen W, Van PG et al. Short-term prognostic value of forced expiratory volume in 1 second divided by height cubed in a prospective cohort of people 80 years and older. BMC Geriatr 2015; 15:15.


Turkeshi E, Vaes B, Andreeva E, Mathei C, Adriaensen W, Van PG et al. Airflow limitation by the Global Lungs Initiative equations in a cohort of very old adults. Eur Respir J 2015; 46(1):123-132.


Multimorbidity measures were poor predictors of adverse events in patients aged ≥80 years: a prospective cohort study

Boeckxstaens, Pauline ; Vaes, Bert ; Van Pottelbergh, Gijs ; De Sutter, An ; Legrand, Delphine ; Adriaensen, Wim ; Matheï, Catharina ; Dalleur, Olivia ; Degryse, Jean-Marie.
Journal of Clinical Epidemiology, Vol. 68, no.2, p. 220-227 (2014). 


Interleukin-6 predicts short-term global functional decline in the oldest old: results from the BELFRAIL study.

Adriaensen W, Matheï C, Vaes B, van Pottelbergh G, Wallemacq P, Degryse J
AGE (Dordr) 2014 Epub 2014 nov 21


No relation between CMV infection and mortality in the oldest old: results from the Belfrail study.

Matheï C, Adriaensen W, Vaes B, Van Pottelbergh G, Wallemacq P, Degryse J.

Age Ageing. 2014 Jul 15. pii: afu094. 


The relationship of multimorbidity with disability and frailty in the oldest patients: A cross-sectional analysis of three measures of multimorbidity in the BELFRAIL cohort.

Boeckxstaens P, Vaes B, Legrand D, Dalleur O, De Sutter A, Degryse JM.

Eur J Gen Pract. 2014 Jul 1:1-6.


Muscle strength and physical performance as predictors of mortality, hospitalization, and disability in the oldest old.

Legrand D, Vaes B, Matheï C, Adriaensen W, Van Pottelbergh G, Degryse JM.

J Am Geriatr Soc. 2014 Jun;62(6):1030-8. doi: 10.1111/jgs.12840


CD4:8 Ratio >5 Is Associated With a Dominant Naive T-Cell Phenotype and Impaired Physical Functioning in CMV-Seropositive Very Elderly People: Results From the BELFRAIL Study.

Adriaensen W, Derhovanessian E, Vaes B, Van Pottelbergh G, Degryse JM, Pawelec G, Hamprecht K, Theeten H, Matheï C.

J Gerontol A Biol Sci Med Sci. 2014 Feb 25.


The glomerular filtration rate estimated by new and old equations as a predictor of important outcomes in elderly patients.

Van Pottelbergh G, Vaes B, Adriaensen W, Matheï C, Legrand D, Wallemacq P, Degryse JM.

BMC Med. 2014 Feb 12;12:27. doi: 10.1186/1741-7015-12-27


Drug prescriptions unadapted to the renal function in patients aged 80 years and older a.

Van Pottelbergh G, Mertens A, Azermai M, Vaes B, Adriaensen W, Matheï C, Wallemacq P, Degryse JM.

Eur J Gen Pract. 2013 Nov 28.


The prevalence of sarcopenia in very old individuals according to the

European consensus definition: insights from the BELFRAIL study

Legrand, D; Vaes, B; Mathei, C; Swine C; Degryse JM

Age and Ageing 2013; doi: 10.1093/ageing/aft128


The relationship between grip strength and muscle mass (MM), inflammatory biomarkers and physical performance in community-dwelling very old persons.

Legrand D, Adriaensen W, Vaes B, Matheï C, Wallemacq P, Degryse J.

Arch Gerontol Geriatr. 2013 Nov-Dec;57(3):345-51. doi: 10.1016/j.archger.2013.06.003. Epub 2013 Jul 4.


Significance of serum immune markers in identification of global functional impairment in the oldest old: cross-sectional results from the BELFRAIL study.

Adriaensen W, Matheï C, van Pottelbergh G, Vaes B, Legrand D, Wallemacq P, Degryse JM.

Age (Dordr). 2013 Jul 3. [Epub ahead of print]


Value of adding natriuretic peptides and electrocardiographic findings to assess the presence of cardiac dysfunction in patients ≥80 years of age.

Vaes B, Boland B, Scavée C, Henrard S, Wallemacq P, Van Pottelbergh G, Matheï C, Pasquet A, Vanoverschelde JL, Rezzoug N, Speybroeck N, Degryse J.

Am J Cardiol. 2013 Apr 15;111(8):1198-208. doi: 10.1016/j.amjcard.2012.12.055. Epub 2013 Feb 1.


The influence of renal function on vitamin D metabolism in the very elderly.

Van Pottelbergh G, Matheï C, Vaes B, Adriaensen W, Gruson D, Degryse JM.

J Nutr Health Aging. 2013 Feb;17(2):107-11. doi: 10.1007/s12603-012-0094-0.


No relation between vitamin D status and physical performance in the oldest old: results from theBelfrail study.

Matheï C, Van Pottelbergh G, Vaes B, Adriaensen W, Gruson D, Degryse JM.

Age Ageing. 2013 Mar;42(2):186-90. doi: 10.1093/ageing/afs186. Epub 2013 Jan 29.

The impact of confounders on the test performance of natriuretic peptides for cardiac dysfunction in subjects aged 80 and older.

Vaes B, Gruson D, Van Pottelbergh G, Pasquet A, Matheï C, Adriaensen W, Rezzoug N, Vanoverschelde JL, Degryse J.

Peptides. 2012 Nov;38(1):118-26. doi: 10.1016/j.peptides.2012.08.020. Epub 2012 Sep 7.


The prevalence and detection of chronic kidney disease (CKD)-related metabolic complications as a function of estimated glomerular filtration rate in the oldest old.

Van Pottelbergh G, Vaes B, Jadoul M, Matheï C, Wallemacq P, Degryse JM.

Arch Gerontol Geriatr. 2012 May-Jun;54(3):e419-25. doi: 10.1016/j.archger.2011.12.010. Epub 2012 Jan 20.


Associations between cytomegalovirus infection and functional impairment and frailty in theBELFRAIL Cohort.

Matheï C, Vaes B, Wallemacq P, Degryse J.

J Am Geriatr Soc. 2011 Dec;59(12):2201-8. doi: 10.1111/j.1532-5415.2011.03719.x. Epub 2011 Nov 7.


The prevalence of cardiac dysfunction and the correlation with poor functioning among the very elderly.

Vaes B, Rezzoug N, Pasquet A, Wallemacq P, Van Pottelbergh G, Matheï C, Vanoverschelde JL, Degryse J.

Int J Cardiol. 2012 Feb 23;155(1):134-43. doi: 10.1016/j.ijcard.2011.07.024. Epub 2011 Aug 11.


Estimating GFR in the oldest old: does it matter what equation we use?

Van Pottelbergh G, Vaes B, Morelle J, Jadoul M, Wallemacq P, Degryse J.

Age Ageing. 2011 May;40(3):401-5. doi: 10.1093/ageing/afr033. Epub 2011 Mar 31.


The BELFRAIL (BFC80+) study: a population-based prospective cohort study of the very elderly in Belgium.

Vaes B, Pasquet A, Wallemacq P, Rezzoug N, Mekouar H, Olivier PA, Legrand D, Matheï C, Van Pottelbergh G, Degryse J.

BMC Geriatr. 2010 Jun 17;10:39. doi: 10.1186/1471-2318-10-39.

National Publications

Vitamine D tekort bij ouderen. 

Van Pottelbergh, G., Matheï, C., Vaes, b., Adriaensen, W., Degryse, J. (2012). Huisarts Nu, 41 (3-4), 125-128.